In a triumph for academic drug discovery, FDA approved a drug developed through SPARK for a life-threatening heart disease. Attruby (acoramidis) was developed through SPARK by co-inventors Dr. Isabella Graef and Dr. Mamoun Alhamadsheh and approved by FDA for the treatment of transthyretin amyloid cardiomyopathy (ATTR-CM). The drug, unchanged from its original academic discovery, transitioned seamlessly into clinical trials without further medicinal chemistry optimization with the help of SPARK and adopted by Eidos Therapeutics and BridgeBio Pharma Inc. This groundbreaking achievement is a testament to the successful SPARK program and the transformative power of academic innovation and interdisciplinary collaboration.
Read moreFounder and Director of Stanford University’s SPARK program Daria Mochly-Rosen shares how she has liberated potential drug discoveries from academic research to industry, and discusses the countless, surprising lessons she has learned along the way.
For manuscript submissions, use this sentence in the acknowledgement:
“Mentored and financially supported by Stanford’s SPARK Translational Research Program”
Daria Mochly-Rosen, PhD Recognized as Recipient of the ACTS Team Science Award
Study shows hydrogel prevents abdominal adhesions in pigs and mice
Video highlights SPARK Africa's commitment to local innovation
The SPARK manual was published by co-founders Daria Mochly-Rosen and Kevin Grimes to help other academic institutions develop their own SPARK Programs.
Learn MoreSPARK is thankful for the continued support of the Maternal and Child Health Research Institute at Stanford. Through their funding, SPARK has been able fund numerous projects in the field of Child and Maternal Health with 11 projects reaching clinic or commercial sectors.
Learn MoreA number of academic institutions have successfully developed their own SPARK programs resulting in a global community of translational scientists who accelerate academic discoveries to patients around the world. Learn more about the work of SPARK Global.
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