SPARK Program in Translational Research

Our Mission: Advance Academic Discoveries from Laboratory to Patient Care

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2nd edition of SPARK book now available

2nd edition of SPARK book now available

The 2nd edition of SPARK’s trusted and comprehensive book on academic drug development is now available! "A Practical Guide to Drug Development in Academia: The SPARK Approach" is written by SPARK's industry advisors and edited by SPARK co-directors Daria Mochly-Rosen and Kevin Grimes. Updated with the latest developments since the 2014 1st edition, this book is a must-have for academic translational scientists. The electronic book is available now and a hard copy version will be released later this month.

Read more and order the eBook
Academic

SPARK Emphasizes New Ways To Bridge The Gap Between Academic Discoveries And Products That Benefit Patients.

SPARK’s mentorship and funding program provides hands-on advising and funding to Stanford affiliates whose product proposals have been accepted for development. Our "SPARKees" benefit from world-class counsel from industry advisors and academic experts who work closely with them to provide the industry knowledge necessary to move their projects from bench to bedside.

About SPARK

Light Your
SPARK!

Academic

Learn About Career Opportunities And Find Your New Passion

The primary purpose of SPARK is education of the greater Stanford community about drug development and advancing discoveries. Beyond attending weekly SPARK lectures, students can take CSB240: A Practical Approach to Drug Discovery and Development, the biannual SPARK Class where students may develop their own SPARK projects. Each year, the class focuses on unmet needs in a particular therapeutic area and interdisciplinary teams are charged with conceiving of and then serially de-risking a novel therapeutic approach for an unmet medical need. Approximately one third of the student projects are licensed or move into clinical study at Stanford. Learn more about our process below

SPARK Scholars

Ignite Your
Own SPARK!

Academic

We’re in the Business of Saving Lives

For many SPARK projects, the optimal path to the clinic is through partnerships with pharmaceutical companies and the development of new startups. With showcases at the Biotechnology Innovation Organization (BIO) Investor Forum and connections with venture capitalists in the region, we do our part to bring SPARK projects forward. As of 2018, thirty-two projects have rolled out into startups and sixteen projects were licensed to existing companies. Some startups raised over $50 million in series A funding and others went public. Half of successful SPARK projects are in clinical studies. Read on to learn more about our successes and potential opportunities.

Commercializing SPARK

The SPARK Opportunities

Academic

SPARK Succeeds With Help From People Like You!

Since 2006, over 50% of SPARK projects have moved to the clinical and commercial sectors through the support of over 200 volunteer industry experts and a few, generous donors. Learn more about how you can support SPARK to advance biomedical research discoveries into new treatments for patients.

Get Involved

Turn SPARK
into a Flame!

TEDMED: SPARKing a new generation in translational research

Founder and Director of Stanford University’s SPARK program Daria Mochly-Rosen shares how she has liberated potential drug discoveries from academic research to industry, and discusses the countless, surprising lessons she has learned along the way.

For manuscript submissions, use this sentence in the acknowledgement: “Mentored and financially supported by Stanford’s SPARK Translational Research Program”

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News

SPARK publishes manuscript in Nature Biotechnology

SPARK publishes manuscript in Nature Biotechnology

Paper details the SPARK program's goals, methods, and metrics

SPARK publishes 2nd edition of Drug Development in Academia

SPARK publishes 2nd edition of Drug Development in Academia

The 2nd edition of SPARK's authoritative book is now available

AIRNA emerges from stealth with $30M financing

AIRNA emerges from stealth with $30M financing

Startup incubated out of SPARK launches to advance RNA editing technology

More From SPARK

Title
SPARK: A Practical Guide to Drug Development in Academia

The SPARK manual was published by co-founders Daria Mochly-Rosen and Kevin Grimes to help other academic institutions develop their own SPARK Programs.

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Title
Supporting Child and Maternal Health

SPARK is thankful for the continued support of the Maternal and Child Health Research Institute at Stanford. Through their funding, SPARK has been able fund numerous projects in the field of Child and Maternal Health with 11 projects reaching clinic or commercial sectors.

Learn More
Title
SPARK Global

A number of academic institutions have successfully developed their own SPARK programs resulting in a global community of translational scientists who accelerate academic discoveries to patients around the world. Learn more about the work of SPARK Global.

Learn More