Filter or Search Current SPARK Projects:
| Indication | Modality | Title/Description |
| Anesthesia | Small Molecule | Safer Small Molecule Anesthetic For High Risk Patients , Infants, Elderly |
Anti-infective, Global Health | Device | Spontaneously Formed Reactive Oxygen Species For Pathogen Disinfection |
Anti-infective, Global Health | Diagnostic | Diagnostic For Prediction Of Severe Dengue |
Anti-infective, Global Health | Small Molecule | Inhibitors For Enterovirus Infection |
Anti-infective, Global Health | Small Molecule | Treatments for Drug-Resistant Tuberculosis |
Anti-infective, Global Health, Rare/Orphan Disease | Small Molecule | Drugs For Treatment of Entamoeba and Naeglaria |
Anti-infective | Imaging Agent | Molecular Imaging for Diagnosis of Bacterial Infections |
Anti-infective, Child/Maternal Health, Global Health, Rare/Orphan Disease | Biologic | Synthetic Antimicrobial Peptoids For The Treatment Of Chronic Suppurative Otitis Media |
Anti-infective, Child/Maternal Health, Global Health, Rare/Orphan Disease | Biologic, Vaccine | Nanoparticle To Treat Chronic Suppurative Otitis Media |
Cardiology, Child/Maternal Health, Rare/Orphan Disease | Imaging Agent | Novel Optical Imaging Agent of Cardiac Conduction System for Use During Heart Surgery |
Cardiovascular | Small Molecule | Novel Treatment for Heart Failure |
Cardiology, Cardiovascular | Biologic, Gene/Cell Therapy | Mitochondrial biogenesis for cardiovascular disease |
Child/Maternal Health, Rare/Orphan Disease, Rheumatology | Diagnostic | Immunophenotyping Of PANS To Inform Treatment |
Child/Maternal Health, Pulmonary, Rare/Orphan Disease | Small Molecule | Inhaled Repurposed Drug To Treat Cystic Fibrosis |
Child/Maternal Health, Platform | Gene/Cell Therapy | Platform To Enhance Therapeutic Gene Targeting |
Child/Maternal Health, Platform | Platform Technology For Delivery of DNA and RNA Therapies |
Child/Maternal Health, Dermatology, Rare/Orphan Disease | Small Molecule | Topical Repurposed Drug For Epidermolysis Bullosa |
Child/Maternal Health, Hematology, Rare/Orphan Disease | Small Molecule | Treatment for Diamond Blackfan Anemia |
Child/Maternal Health, Neurology | Prevention of post-hemorrhagic hydrocephalus in severe neonatal intraventricular hemorrhage |
Child/Maternal Health, Opthalmology, Rare/Orphan Disease | Biologic | Bioactive Collagen Filler For Sutureless Corneal Tissue Reconstruction |
Child/Maternal Health, Pregnancy, Rare/Orphan Disease | Biologic | Platelet Rich Plasma For Patients With Recurrent Implantation Failure |
Child/Maternal Health, Congenital, Pulmonary, Rare/Orphan Disease | Biologic | CRISPRd upper airway stem cell for Cystic Fibrosis |
Rare/Orphan Disease | Gene/Cell Therapy | Therapeutic transcriptome engineering |
Child/Maternal Health, Congenital | Gene/Cell Therapy | Developing Integrases as next-generation Gene Therapies |
Congenital, Dermatology | Gene/Cell Therapy | iPS-derived skin sheet product for dystrophic epidermolysis bullosa |
Dermatology | Small Molecule | Therapeutic for Skin Cancers |
Dermatology | Small Molecule | Therapeutic For Progressive Systemic Sclerosis |
Endrocrinology, Immunology, Metabolic | Biologic | Developing Biologics for Diabetes |
Endrocrinology | Biologic | Improved Insulin formulation for the Treatment of diabetes |
Endrocrinology, Global Health | Small Molecule | Detection And Treatment Of Insulin Resistance |
Gastroenterology, Metabolic | Small Molecule | Novel formulation to prevent post-endoscopic retrograde cholangiopancreatography pancreatitis |
Gastroenterology, Surgery | Small Molecule | Small molecule to prevent abdominal adhesion formation |
Child/Maternal Health, Hematology | Small Molecule | Treatment of Diamond Blackfan Anemia |
Gastroenterology, Hepatology, Metabolic | Small Molecule | Small molecule inhibition to prevent fibrosis in NASH |
Hepatology | Small Molecule | Small Molecule To Prevent Progression Of Non Alcoholic Steatohepatitis |
Immunology | Diagnostic | Profiling of immune responses to SARS-CoV-2 vaccination |
Immunology | Small Molecule | Natural Product Flavanoids For Modulating Surgical Immune Response |
Immunology | Engineered Mesechymal Stem Cells For Immune Tolerance In Islet Transplant |
Immunology | MH-PSCs For Immune Suppression Free Transplant |
Metabolic | Small Molecule | Small Molecule Activator To Treat Mitochondrial Disorders |
Metabolic | Small Molecule | Small Molecule Inducer Of Beta Cell Regeneration |
Neurology | Small Molecule | Novel Diagnostic/Therapeutic For Autism |
Neurology, Rare/Orphan Disease | Small Molecule | Inhibitors Of RNA Lariat Debranching For ALS & HIV |
Aging, Neurology | Small Molecule | Targeting Immune Function in Age-Associated diseases |
Neurology | Small Molecule | Small Molecule Inhibitor For Treatment Of Neurodegenerative Disease |
Neurology | Small Molecule | Small Molecule For The Treatment Of Parkinson’s Disease |
Neurology | Device | Precision Care For Autism Through Wearable Artificial Intelligence |
Neurology | Imaging Agent | PET Imaging Of Synapses In Schizophrenia |
Neurology | Small Molecule | Open-label Pilot Study Of A Small Molecule for Children With Autism |
Oncology | Small Molecule | Small Molecule for Cancers of Endodermal and Ectodermal Origin |
Oncology | Diagnostic | Liquid biopsy-based Detection of Biomarkers for Early cancer detection |
Oncology, Rare/Orphan Disease | Small Molecule | Small Molecule Activators For The Treatment Of Chronic Dry Mouth |
Oncology, Rare/Orphan Disease | Small Molecule | Topical Treatment For Resistant Basal Cell Carcinoma |
Oncology | Imaging Agent | Clinical Development and Commercialization of a Metabolic Imaging Agent for Glioblastoma |
Oncology | Small Molecule | Targeted Therapy For Melanoma |
Immunology, Metabolic, Oncology | Biologic | Therapeutic Antibodies for the Treatment of cancers associated with Obesity |
Oncology | Biologic | Topical Biologic To Prevent Radiation-induced Oral Mucositis |
Oncology | Small Molecule | Small Molecule To Restore A Global Immune Response Against Cancer |
Oncology | Small Molecule | Small Molecule Inhibitors For Colorectal Cancer Stem Cells |
Oncology | Small Molecule | Small Molecule For Chemotherapy-induced Pheripheral Nuerophathy |
Oncology | Small Molecule | Selective Compounds For Triple-negative Breast Cancer |
Child/Maternal Health, Immunology, Oncology | Biologic, Gene/Cell Therapy, Small Molecule | Drug-controlled CAR T cells for the treatment of pediatric leukemia |
Oncology | Small Molecule | Novel Treatment For Kidney Cancer |
Oncology | Small Molecule | Small Molecule Inhibition of Cell Proliferation through Disruption of Protein Interactions |
Plastic Surgery | Enhancing Fat Graft Retention Using Injectable Macroporous Matrices |
Platform | Diagnostic | Multiplexed Pathogen Detection with Spectrally Encoded Beads |
Platform | Diagnostic | Rapid detection of common cell-culture irregularities |
Oncology, Pulmonary | Biologic | Antibody for treating Lung cancer and Fibrotic Lung diseases |
Next Steps
If you want to know more about specific SPARK projects or SPARK as a whole, please feel free to do the following:
Contact the BD Manager
Past Successes
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