Current SPARK Projects

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Indication Modality Title/Description
Anesthesia Small Molecule Safer Small Molecule Anesthetic For High Risk Patients , Infants, Elderly
Anti-infective, Child/Maternal Health, Global Health, Rare/Orphan Disease Biologic, Vaccine Nanoparticle To Treat Chronic Suppurative Otitis Media
Anti-infective, Child/Maternal Health, Global Health, Rare/Orphan Disease Biologic Synthetic Antimicrobial Peptoids For The Treatment Of Chronic Suppurative Otitis Media
Anti-infective, Global Health Vaccine Liver-stage Malaria Vaccine
Anti-infective, Global Health Diagnostic Diagnostic For Prediction Of Severe Dengue
Anti-infective, Global Health Small Molecule Inhibitors For Enterovirus Infection
Anti-infective, Global Health Small Molecule Treatments for Drug-Resistant Tuberculosis
Anti-infective, Global Health Small Molecule Drugs For Treatment of Entamoeba and Naeglaria
Anti-infective, Global Health Device Spontaneously Formed Reactive Oxygen Species For Pathogen Disinfection
Cardiology, Child/Maternal Health, Rare/Orphan Disease Imaging Agent Novel Optical Imaging Agent of Cardiac Conduction System for Use During Heart Surgery
Cardiovascular Small Molecule Novel Treatment for Heart Failure
Child/Maternal Health, Platform Platform Technology For Delivery of DNA and RNA Therapies
Child/Maternal Health, Platform Gene/Cell Therapy Platform To Enhance Therapeutic Gene Targeting
Child/Maternal Health, Dermatology, Rare/Orphan Disease Small Molecule Topical Repurposed Drug For Epidermolysis Bullosa
Child/Maternal Health, Hematology, Rare/Orphan Disease Small Molecule Treatment for Diamond Blackfan Anemia
Child/Maternal Health, Opthalmology, Rare/Orphan Disease Biologic Bioactive Collagen Filler For Sutureless Corneal Tissue Reconstruction
Child/Maternal Health, Congenital, Rare/Orphan Disease Small Molecule RNA Treatment for Telomere Failure
Child/Maternal Health, Pregnancy, Rare/Orphan Disease Biologic Platelet Rich Plasma For Patients With Recurrent Implantation Failure
Child/Maternal Health, Rare/Orphan Disease, Rheumatology Diagnostic Immunophenotyping Of PANS To Inform Treatment
Child/Maternal Health, Pulmonary, Rare/Orphan Disease Small Molecule Inhaled Repurposed Drug To Treat Cystic Fibrosis
Dermatology Small Molecule Therapeutic For Progressive Systemic Sclerosis
Dermatology Small Molecule Therapeutic for Skin Cancers
Endrocrinology, Global Health Small Molecule Detection And Treatment Of Insulin Resistance
Hepatology Small Molecule Small Molecule To Prevent Progression Of Non Alcoholic Steatohepatitis
Immunology Small Molecule Natural Product Flavanoids For Modulating Surgical Immune Response
Immunology Engineered Mesechymal Stem Cells For Immune Tolerance In Islet Transplant
Immunology MH-PSCs For Immune Suppression Free Transplant
Metabolic Small Molecule Small Molecule Activator To Treat Mitochondrial Disorders
Metabolic Small Molecule Small Molecule Inducer Of Beta Cell Regeneration
Neurology, Rare/Orphan Disease Small Molecule Inhibitors Of RNA Lariat Debranching For ALS & HIV
Neurology Small Molecule Novel Diagnostic/Therapeutic For Autism
Neurology Small Molecule Open-label Pilot Study Of A Small Molecule for Children With Autism
Neurology Imaging Agent PET Imaging Of Synapses In Schizophrenia
Neurology Device Precision Care For Autism Through Wearable Artificial Intelligence
Neurology Small Molecule Small Molecule For The Treatment Of Parkinson’s Disease
Neurology Small Molecule Small Molecule Inhibitor For Treatment Of Neurodegenerative Disease
Oncology Small Molecule Small Molecule To Restore A Global Immune Response Against Cancer
Oncology Small Molecule Targeted Therapy For Melanoma
Oncology Biologic Topical Biologic To Prevent Radiation-induced Oral Mucositis
Oncology, Rare/Orphan Disease Small Molecule Small Molecule Activators For The Treatment Of Chronic Dry Mouth
Oncology, Rare/Orphan Disease Small Molecule Topical Treatment For Resistant Basal Cell Carcinoma
Oncology Small Molecule Small Molecule Inhibition of Cell Proliferation through Disruption of Protein Interactions
Oncology Small Molecule Novel Treatment For Kidney Cancer
Oncology Small Molecule Selective Compounds For Triple-negative Breast Cancer
Oncology Small Molecule Small Molecule For Chemotherapy-induced Pheripheral Nuerophathy
Oncology Small Molecule Small Molecule Inhibitors For Colorectal Cancer Stem Cells
Plastic Surgery Enhancing Fat Graft Retention Using Injectable Macroporous Matrices


 
Next Steps

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