Members
Indication:
PsychiatryModality:
DiagnosticJacob Ballon , MD
Clinical ProfessorJacob S. Ballon, M.D., M.P.H. specializes in the treatment of people with psychotic disorders including schizophrenia. He is the Co-Director of the INSPIRE Clinic at Stanford which provides interdisciplinary care for people experiencing psychosis. He is also the medical director of H2 acute inpatient unit at Stanford Hospital. Dr. Ballon completed his residency at Stanford in 2009 and a Schizophrenia Research Fellowship at Columbia University in 2011.
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Child/Maternal HealthModality:
Biologic, DiagnosticLusine Aghajanova , MD, PhD
Clinical Assistant ProfessorDr. Lusine Aghajanova is double board certified in ObGyn and in Reproductive Endocrinology and Infertility (REI), a Clinical Assistant Professor of ObGyn and REI at Stanford University and a member of Maternal & Child Health Research Institute (MCHRI). Her clinical interests include endometrial/uterine aspects of fertility and assisted reproduction. Dr. Aghajanova is a respected researcher in the field of endometrial receptivity, implantation and endometriosis, endometrial regeneration, with >70 peer-reviewed publications. She is active peer-reviewer for over 12 professional journals, is currently as Associate Editor for Human Reproduction, and serves on Editorial Board for Fertility&Sterility Reports and for JARG
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Anti-infective, Immunology, Other, PregnancyModality:
Antibiotic, Biologic, Imaging Agent, Small MoleculeSiavash Azari , PhD
Postdoctoral ScholarI am a postdoctoral researcher from Tehran, Iran. I joined Dr. Shirit Einav's lab in September 2021. The focus of my research is on developing novel, selective inhibitors of the Numb-Associated Kinases (NAK) as broad-spectrum antivirals. These inhibitors are potent against multiple unrelated viruses which our lab has shown rely on members of the NAK family for effective replication, including dengue virus (DENV), Venezuelan Equine Encephalitis Virus (VEEV) and SARS-CoV2. I am also interested in discovering novel substrates of NAKs and better characterizing the signaling pathways they regulate in cell biology and viral infection. My PhD dissertation under Dr. Stephanie Seveau's supervision at The Ohio State University was focused on the role of fetal placental macrophages in mother-to-fetus transmission of listeriosis. My master’s thesis at Qazvin University of Medical Sciences in Qazvin, Iran, was on a modified derivative of rotavirus toxin NSP4 as a candidate for vaccine production. I enjoy doing translational research that can be used as a stepping stone toward the development of therapeutics to battle human diseases. My hobbies are: Learning foreign languages, cooking, traveling, exploring food from different cultures, and inventing new cocktails with tequila! Fun fact: To do research at Stanford, I moved by driving 2,500 miles across the country from Columbus, Ohio to San Jose, California, and had the greatest road trip of my life!
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Indication:
Otolaryngology (ENT)Modality:
AntiobioticBrian Bacacao , PhD
Research AssociateBrian Bacacao is a research associate specializing in Microbiology. He joined the Santa Maria lab in 2019 after completing his bachelor of science in Biology at Arizona State University. His research interests are in biotechnology and drug discovery.
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Child/Maternal Health, Gene Therapy, Immunology, Rare/Orphan DiseasesModality:
Diagnostic, Gene/Cell TherapyRosa Bacchetta , MD
Associate ProfessorPhysician scientist, pediatric immunologist by training. Research focused on regulatory T cells and immune tolerance. Expert in autoimmune genetic diseases and other Tregopathies. IND sponsor for an engineered Treg cell product for Phase 1 trial in IPEX syndrome, a novel orphan drug designated therapy, about to begin at Stanford. Continuing to investigate immune regulatory disorders, improve diagnostics and developing definitive treatments based on cell/gene therapy. Former SPARK Scholar, Member of CDCM and MCHRI.
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Indication:
Anti-infective , Child/Maternal Health , Immunology , NeurologyModality:
Antibiotic , Cell Therapy , Device , Small MoleculeAnnelise Barron , PhD
Associate ProfessorAnnelise E. Barron is the W.M. Keck Associate Professor of Bioengineering at Stanford University. She was trained as a chemical engineer at the Univ. of Washington (B.S.) and U.C. Berkeley (Ph.D.), and was a Pharmaceutical Chemistry postdoc with Prof. Ken A. Dill (UCSF) and Dr. Ronald N. Zuckermann (Chiron Corp.). She has served on the faculty at Stanford since 2007, and prior to that, served on the Chemical & Biological Engineering faculty of Northwestern University in Evanston, IL for 10 years (1997-2007). In Fall 2020, Dr. Barron was awarded the NIH Pioneer Award, through NIH/NIA, for Alzheimer's disease research.
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Anesthesia , Child/Maternal Health , Global Health , OtherModality:
Small MoleculeEdward Bertaccini , MD
ProfessorDr. Bertaccini is a native of San Jose, California. He graduated Summa Cum Laude in Biochemistry and Quantum Physics from UC Davis and obtained his MD from St. Louis University. He completed his internship at the Santa Clara Valley Medical Center, and his anesthesiology residency and ICU fellowship at Stanford. He is currently a Professor of Anesthesiology and ICU Medicine at Stanford and the Palo Alto VA. He is internationally recognized for research on the molecular modeling of anesthetic action. He has played an integral role in teams that have achieved national recognition for cardiac surgery and intensive care outcomes
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Indication:
Gene Therapy, OtherModality:
Gene/Cell TherapyVivek Bhalla , MD
Associate ProfessorDr. Bhalla is an adult nephrologist and a physician-scientist at the Stanford University School of Medicine and the founding director of the Stanford Hypertension Center. His laboratory studies molecular mechanisms of chronic kidney disease. He uses a combination of transgenic mice, renal physiology, and molecular biology to address research questions. In collaboration with other SPARK members, Dr. Bhalla has worked on gene editing of renal epithelial cells and targeted kidney delivery with applications for several kidney diseases, including polycystic kidney disease, the most common form of monogenic disease in humans.
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Indication:
ImmunologyModality:
Small MoleculeHelen Blau , PhD
ProfessorBlau's research area is regenerative medicine with a focus on stem cells. She is world-renowned for her work on nuclear reprogramming and demonstration of the plasticity of cell fate using cell fusion. These studies provided the scientific underpinnings for mammalian cloning and induced pluripotent stem cells. Blau also led the field with novel approaches to treating muscle damage due to disease, injury, or aging. She pioneered the design of biomaterials to mimic the in vivo microenvironment and direct stem cell fate. A major focus of her current work is the rejuvenation of aged tissues.
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Metabolic , OncologyModality:
Biologic , Small MoleculeCecelia Brown , MS
PhD Student in BiologyHello! I am a fourth-year graduate student in the Skotheim Lab in the Department of Biology. Our lab studies cell cycle control and cell size. Within this realm, I am interested in developing compounds that disrupt progression through the cell cycle. Prior to coming to Stanford, I went to San Francisco State University for Masters and San Jose State University for my undergraduate degree. I was born and raised here in the Bay Area and my hobbies outside of science include, reading, cooking, winter sports, tennis, and exploring the outdoors.
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Indication:
OncologyModality:
Small MoleculeChris Chen , MD
Assistant ProfessorDr. Chen is a board-certified, fellowship-trained specialist in oncology and hematology. He is also an Assistant Professor in the Division of Oncology in the Department of Medicine at Stanford University School of Medicine.
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Indication:
MetabolicModality:
DeviceChehong Chen , PhD
Senior Research ScientistSenior Research Scientist focusing on diseases caused by aldehyde toxicity and aldehyde metabolism. Interested in the role of different ALDH gene member and their variations in different ethnic populations. Successfully discovered small molecule activators and modulators for different ALDH isozymes. Current efforts also involve public health eduaction, awareness of alcohol flushing and prevention of alcohol-induced upper aerodigestive track cancer among the East Asians.
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Indication:
Global Health , Immunology , OncologyModality:
Cell Therapy , Device , DiagnosticSeth Cordts
Graduate StudentI am a PhD student working in the Sindy Tang lab on biomedical microdevices for generating unifromly-sized micro cancer organoids from patient tumor biopsies. We hope to use this device and the organoids for personalized medicine, and drug testing/discovery.
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Indication:
OncologyModality:
Small MoleculeGerald Crabtree , MD
Professor of Pathology and of Developmental BiologyOur laboratory is interested in chromatin regulation and its role in neurodevelopmental diseases and cancer. We focus primarily on the SWI/SNF-like BAF ATP dependent chromatin remodeler.
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Indication:
Anesthesia, NeurologyModality:
Small MoleculeFrances Davies , PhD
Program OfficerI am a Ph.D. neuropharmacologist who has used electrophysiological, biochemical, behavior techniques to investigate mechanism and effects of many of the drugs used in anesthesia. Throughout my career I have made contributions to the fields of benzodiazepines and GABAA receptors, mechanisms of serotonergic and opiate transmission, and in mechanism of action of analgesia and sedation of acute and chronic administration of alpha-2 adrenergic agonists and of nitrous oxide. At Molecular Research Institute as the Director of Experimental Program I worked with computational chemists to design new opiate and benzodiazepine drugs using the same skills I have been using for this
Indication:
ImmunologyModality:
AntiboyCristabelle De Souza , PhD
Postdoctoral ScholarPostdoctoral Fellow studying immune mechanisms governing the progression of fibrosis and cancer with an ultimate goal of developing a therapeutic antibody to reverse fibrosis in the context of HCC, liver cirrhosis, NAFLD and NASH.
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Indication:
ImmunologyModality:
AntibodyQiwen Deng , PhD
Postdoctoral Scholar2021-now Stanford University Postdoc 2013-2019 Peking University Ph.D. Molecular Cell Biology
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Child/Maternal Health , Pregnancy , Rare/Orphan DiseaseModality:
BiologicJustin Donnelly
Graduate StudentI am a PhD student in the Chemistry Department and the Bertozzi Lab. I joined my SPARK team through the graduate course taught by SPARK and am very excited to learn more about translational medicine and how I can better position my research to produce clinical products that benefit patients.
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Anti-infective , Global Health , ImmunologyModality:
Small MoleculeShirit Einav , MD
Associate ProfessorShirit Einav is an Associate Professor of Medicine (infectious diseases) and or Microbiology & Immunology at Stanford and a Biohub Investigator. She leads an interdisciplinary research program focused on understanding the roles of virus-host interactions in viral infection and disease pathogenesis. This program is combined with translational efforts to apply this knowledge for the development of broad-spectrum host-centered antiviral approaches to combat emerging viral infections and means to predict disease progression. Several of Shirit’s drug develop
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Indication:
OtherModality:
Device, DiagnosticPedram Fatehi , MD
Clinical Associate ProfessorI'm a clinician and an educator. I'm actively practicing in inpatient and outpatient settings: ICU, hospital wards, nephrology/hypertension clinics. I have formal teaching responsibilities for college undergraduates, pre-clinical medical students, clerks, house officers, and clinical fellows in nephrology and critical care medicine. The unifying theme in my work is the application of integrative physiology.
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Indication:
OncologyModality:
Small MoleculeZhiping Feng , PhD
Postdoctoral ScholarPostdoc, Stanford University; Chemical and Systems BIology 2017- Ph.D., UCLA; Molecular, Cellular and Integrative Physiology 2010-2016 B.S., Nankai University; Pharmacy 2006-2010
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Indication:
Neurology , Rare/Orphan DiseaseModality:
Biologic , Gene/Cell Therapy , Small MoleculeYanan Feng , PhD
Senior Research ScientistDr. Yanan Feng is a Senior Research Scientist working at Dr. Stanley N. Cohen’s lab in the Department of Genetics, Stanford University. She earned her PhD degree in the Cancer Biology Program from the Stanford University. For the past few years, her research has been focusing on the functions of a transcription elongation factor SUPT4H1 which is required for the transcription of the expanded nucleotide repeats.Such repeats are present and the cause of many genetic neurodegenerative diseases such as Huntington’s Disease and ALS. Targeting SUPT4H1 provides potential therapeutic methods to those diseases which have no cure currently.
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Indication:
Oncology, PediatricsModality:
Cell Therapy, Gene/Cell Therapy, Small MoleculePaul Finn , PhD
Postdoctoral ScholarPassionate and hardworking scientist with years of hands-on laboratory experience in chemistry (10+ years), chemical biology (5+ years), and bioengineering (3+ years) with a deep understanding of molecular interactions and immune cell receptor design.
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Indication:
GastroenterologyModality:
Small MoleculeBill Fitch , PhD
Visiting ProfessorPhd in chemistry. 47 years experience in analytical chemistry, mass spectrometry and drug metabolism
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Indication:
PlatformModality:
Device, DiagnosticPolly Fordyce , PhD
Assistant ProfessorThe Fordyce lab leverages microfluidics for high-throughput and quantitative biophysics, biochemistry, and single-cell biology. One such platform (MRBLEs) generates and uses spectrally encoded beads for multiplexed measurement of protein/protein interactions and nucleic acid hybridization. In recent work, we have been using MRBLEs for fast, low cost, and multiplexed diagnosis of pathogens in sepsis.
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